This is the secondary rhythm guitar. It isn't much more difficult than Guitar 1 but you do need to know your muting techniques! The song is in D tuning, which means tuning each string down by 2 frets to the following:
D tuning: Low D : G : C : F : A : D
Intro / Verse - While Guitar 1 does the intro, this guitar gets stuck straight into the main verse riff. It's just the top half of 3 chords (F# minor - E major - D major), but these are played on offbeats, with muting between strikes. Use both hands to mute - as explained in this video and this lesson. You can also thumb-mute the lowest 3 strings to stop them sounding while you play.
Chorus - For the chorus this guitar plays a 'sort-of' melody. The key thing here is to mute consistently between each note. You can use alternate pick strokes (down / up) if you find it easier. Notice that the second chorus is played slightly differently. It is nearly the same, except for the start and a few notes are played differently.
Interlude - This guitar plays the exact same lick as guitar 1. The difference is only that this guitar doesn't join in until halfway through the interlude.
Outro - Just repeat Chorus 1 twice until the song ends!